Description
Product Characteristics:
Aliases: ATP receptor antibody, H.sapiens mRNA for ATP receptor antibody, P2 RX1 antibody, P2rx1 antibody, P2RX1 protein antibody, P2RX1_HUMAN antibody, P2X purinoceptor 1 antibody, P2X receptor subunit 1 antibody, P2X1 antibody, P2X1 receptor antibody, Purinergic receptor antibody, Purinergic receptor P2X ligand gated ion channel 1 antibody, Purinergic receptor P2X1 antibody
Target Information: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill. [provided by RefSeq, Jul 2008]